 | Koninklijke Boom uitgevers | Meppel, drenthe, netherlands | 110 | publishing | 1841 | |
 | Mandrino | Meppel, drenthe, netherlands | 3 | information technology and services | 2018 | |
 | Kienergie | Meppel, drenthe, netherlands | 1 | semiconductors | - | |
 | Enbizz BV | Meppel, drenthe, netherlands | 1 | oil and energy | 2013 | |
 | Das Idee. Inspireert, creëert, accelereert | Meppel, drenthe, netherlands | 3 | marketing and advertising | 2002 | |
 | autorent direct / shortlease direct | meppel, drenthe, netherlands | - | automotive | 2005 | |
 | inreda project + interieur | meppel, drenthe, netherlands | - | furniture | - | |
| king servers | meppel, drenthe, netherlands | - | internet | 2008 | |
| woonconcept | meppel, drenthe, netherlands | - | civic and social organization | - | |
 | dantuma - wegkamp b.v. | meppel, drenthe, netherlands | - | construction | 2010 | |
| sem-productions | meppel, drenthe, netherlands | - | accounting | 2007 | |
 | bariet ten brink bv | meppel, drenthe, netherlands | - | printing | 2016 | |
| administratie- en adviesbureau lijster | meppel, drenthe, netherlands | - | accounting | 1980 | |
| amigo promotion bv | meppel, drenthe, netherlands | - | marketing and advertising | 1989 | |
| woonscan | meppel, drenthe, netherlands | - | real estate | - | |
| koo meppel | meppel, drenthe, netherlands | - | civic and social organization | 2009 | |
| mischa brendel | meppel, drenthe, netherlands | - | media production | - | |
| focus-jeugd & gezin | meppel, drenthe, netherlands | - | hospital and health care | 2013 | |
| ivo de jong architect | meppel, drenthe, netherlands | - | architecture and planning | 2014 | |
| magnus stellar | meppel, drenthe, netherlands | - | broadcast media | 2019 | |
